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ifnar2 shrna  (Santa Cruz Biotechnology)


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    Structured Review

    Santa Cruz Biotechnology ifnar2 shrna
    Figure 4. Knockdown of IFNARs rescues defective DS microglia in chimeras (A) A schematic diagram showing the experimental design. This drawing was created using BioRender.com. (B) qPCR analysis of IFNAR1 and <t>IFNAR2</t> mRNA expression in chimeras at week 8 and month 4 (n = 4–5 mice/group). (C and D) Flow cytometry analysis and quantification of IFNAR1 and IFNAR2 expression in 4-month-old chimeras (n = 4).
    Ifnar2 Shrna, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 92/100, based on 3 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ifnar2+shrna/IFN-%CE%B1%2F%CE%B2R%CE%B2+siRNA/pm35803230-892-14-27
    Average 92 stars, based on 3 article reviews
    ifnar2 shrna - by Bioz Stars, 2026-09
    92/100 stars

    Images

    1) Product Images from "Type-I-interferon signaling drives microglial dysfunction and senescence in human iPSC models of Down syndrome and Alzheimer's disease."

    Article Title: Type-I-interferon signaling drives microglial dysfunction and senescence in human iPSC models of Down syndrome and Alzheimer's disease.

    Journal: Cell stem cell

    doi: 10.1016/j.stem.2022.06.007

    Figure 4. Knockdown of IFNARs rescues defective DS microglia in chimeras (A) A schematic diagram showing the experimental design. This drawing was created using BioRender.com. (B) qPCR analysis of IFNAR1 and IFNAR2 mRNA expression in chimeras at week 8 and month 4 (n = 4–5 mice/group). (C and D) Flow cytometry analysis and quantification of IFNAR1 and IFNAR2 expression in 4-month-old chimeras (n = 4).
    Figure Legend Snippet: Figure 4. Knockdown of IFNARs rescues defective DS microglia in chimeras (A) A schematic diagram showing the experimental design. This drawing was created using BioRender.com. (B) qPCR analysis of IFNAR1 and IFNAR2 mRNA expression in chimeras at week 8 and month 4 (n = 4–5 mice/group). (C and D) Flow cytometry analysis and quantification of IFNAR1 and IFNAR2 expression in 4-month-old chimeras (n = 4).

    Techniques Used: Knockdown, Expressing, Flow Cytometry

    Related Articles

    shRNA:

    Article Title: Type-I-interferon signaling drives microglial dysfunction and senescence in human iPSC models of Down syndrome and Alzheimer's disease.
    Article Snippet: .. Cell Stem Cell 29, 1135–1153.e1–e8, July 7, 2022 e6 shRNA knockdown IFNAR1 shRNA (sc-35637-V), IFNAR2 shRNA (sc-40091-V), and non-targeting control shRNA (sc-108080) lentiviral particles were purchased from Santa Cruz Biotechnology. ..

    Article Title: Type I Interferon Signaling Drives Microglial Dysfunction and Senescence in Human iPSC Models of Down Syndrome and Alzheimer’s Disease
    Article Snippet: .. IFNAR1 shRNA (sc-35637-V), IFNAR2 shRNA (sc-40091-V), and non-targeting control shRNA (sc-108080) lentiviral particles were purchased from Santa Cruz Biotechnology. ..

    Knockdown:

    Article Title: Type-I-interferon signaling drives microglial dysfunction and senescence in human iPSC models of Down syndrome and Alzheimer's disease.
    Article Snippet: .. Cell Stem Cell 29, 1135–1153.e1–e8, July 7, 2022 e6 shRNA knockdown IFNAR1 shRNA (sc-35637-V), IFNAR2 shRNA (sc-40091-V), and non-targeting control shRNA (sc-108080) lentiviral particles were purchased from Santa Cruz Biotechnology. ..

    Control:

    Article Title: Type-I-interferon signaling drives microglial dysfunction and senescence in human iPSC models of Down syndrome and Alzheimer's disease.
    Article Snippet: .. Cell Stem Cell 29, 1135–1153.e1–e8, July 7, 2022 e6 shRNA knockdown IFNAR1 shRNA (sc-35637-V), IFNAR2 shRNA (sc-40091-V), and non-targeting control shRNA (sc-108080) lentiviral particles were purchased from Santa Cruz Biotechnology. ..

    Article Title: Type I Interferon Signaling Drives Microglial Dysfunction and Senescence in Human iPSC Models of Down Syndrome and Alzheimer’s Disease
    Article Snippet: .. IFNAR1 shRNA (sc-35637-V), IFNAR2 shRNA (sc-40091-V), and non-targeting control shRNA (sc-108080) lentiviral particles were purchased from Santa Cruz Biotechnology. ..



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    Figure 4. Knockdown of IFNARs rescues defective DS microglia in chimeras (A) A schematic diagram showing the experimental design. This drawing was created using BioRender.com. (B) qPCR analysis of IFNAR1 and <t>IFNAR2</t> mRNA expression in chimeras at week 8 and month 4 (n = 4–5 mice/group). (C and D) Flow cytometry analysis and quantification of IFNAR1 and IFNAR2 expression in 4-month-old chimeras (n = 4).
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    ifnar2 shrna gfp control packaging lentivirus  (Millipore)
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    Figure 4. Knockdown of IFNARs rescues defective DS microglia in chimeras (A) A schematic diagram showing the experimental design. This drawing was created using BioRender.com. (B) qPCR analysis of IFNAR1 and <t>IFNAR2</t> mRNA expression in chimeras at week 8 and month 4 (n = 4–5 mice/group). (C and D) Flow cytometry analysis and quantification of IFNAR1 and IFNAR2 expression in 4-month-old chimeras (n = 4).
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    Image Search Results


    Figure 4. Knockdown of IFNARs rescues defective DS microglia in chimeras (A) A schematic diagram showing the experimental design. This drawing was created using BioRender.com. (B) qPCR analysis of IFNAR1 and IFNAR2 mRNA expression in chimeras at week 8 and month 4 (n = 4–5 mice/group). (C and D) Flow cytometry analysis and quantification of IFNAR1 and IFNAR2 expression in 4-month-old chimeras (n = 4).

    Journal: Cell stem cell

    Article Title: Type-I-interferon signaling drives microglial dysfunction and senescence in human iPSC models of Down syndrome and Alzheimer's disease.

    doi: 10.1016/j.stem.2022.06.007

    Figure Lengend Snippet: Figure 4. Knockdown of IFNARs rescues defective DS microglia in chimeras (A) A schematic diagram showing the experimental design. This drawing was created using BioRender.com. (B) qPCR analysis of IFNAR1 and IFNAR2 mRNA expression in chimeras at week 8 and month 4 (n = 4–5 mice/group). (C and D) Flow cytometry analysis and quantification of IFNAR1 and IFNAR2 expression in 4-month-old chimeras (n = 4).

    Article Snippet: Cell Stem Cell 29, 1135–1153.e1–e8, July 7, 2022 e6 shRNA knockdown IFNAR1 shRNA (sc-35637-V), IFNAR2 shRNA (sc-40091-V), and non-targeting control shRNA (sc-108080) lentiviral particles were purchased from Santa Cruz Biotechnology.

    Techniques: Knockdown, Expressing, Flow Cytometry